Hand Foot and Mouth Disease is a bugger. I will tell you that. My daughter had it at 18 months. Some of the signs to look for are unwillingness to eat, because of sores in the mouth, rash on the hands, feet and buttocks. The poor little things are miserable. This is caused by a virus, so antibiotics will not help this infection. You just have to wait it out.
Symptoms include the mouth sores and rash as I stated, fever, sore throat, and a general crappy feeling. Children might not eat much, but they need to still be drinking fluids so that they don't become dehydrated. Also make sure to wash their hands often and any contaminated surfaces including toys. Your doctor might tell you to give them something for the pain, likely tylenol or ibuprofen, and also maybe something to numb the mouth.
FYI: It can be spread to adults so don't be sharing cups, utensils, etc. just because you are old!
For more information visit the CDC at http://www.cdc.gov/hand-foot-mouth/about/index.html
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